Trial Profile

Phase II Clinical Trial of HSV G207 With a Single 5 Gy Radiation Dose in Children With Recurrent High-Grade Glioma

Status: Withdrawn prior to enrolment

Phase of Trial: Phase II

Latest Information Update: 13 Feb 2026

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At a glance

Drugs G 207 (Primary)
Indications Anaplastic astrocytoma; Glioblastoma; Glioma
Focus Registrational; Therapeutic Use

Most Recent Events

10 Feb 2026 Status changed from suspended to withdrawn prior to enrolment, because the federal funding for this trial was lost and PBTC-061 was permanently closed on 24 Oct 2025 with no patients enrolled. The operations will be stopped in March 2026.
04 Sep 2025 Status changed from recruiting to suspended, because current funding from Pediatric Brain Tumor Consortium (PBTC) expires on March 31, 2026 after which PBTC plans to cease operations.
26 Jun 2025 Planned initiation date changed from 1 Jul 2025 to 1 Sep 2025.

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