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A Single-arm, Multicenter Phase II Clinical Study to Evaluate the Efficacy and Safety of Tyrosine Kinase Inhibitor (TKI) in Combination With Anti-PD-1 Antibody in TKI-responded Microsatellite Stability/Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Adenocarcinoma.

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A Single-arm, Multicenter Phase II Clinical Study to Evaluate the Efficacy and Safety of Tyrosine Kinase Inhibitor (TKI) in Combination With Anti-PD-1 Antibody in TKI-responded Microsatellite Stability/Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Adenocarcinoma.

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 08 Sep 2023

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At a glance

  • Drugs Fruquintinib (Primary) ; Regorafenib (Primary) ; Toripalimab (Primary)
  • Indications Adenocarcinoma; Colorectal cancer; Liver metastases
  • Focus Therapeutic Use
  • Acronyms TRAP

    • Most Recent Events

    • 13 Sep 2022 Preliminary results (n=35) presented at the 47th European Society for Medical Oncology Congress.
    • 28 Sep 2021 Planned primary completion date changed from 31 Jul 2021 to 31 Jul 2022.
    • 12 Aug 2020 Status changed from not yet recruiting to recruiting.

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