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A Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients With COVID-19

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Trial Profile

A Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients With COVID-19

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 09 May 2024

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At a glance

  • Drugs Amubarvimab/romlusevimab-Brii-Biosciences (Primary) ; Bamlanivimab (Primary) ; Cilgavimab/tixagevimab (Primary) ; Cilgavimab/tixagevimab (Primary) ; Ensovibep (Primary) ; Sotrovimab (Primary) ; Remdesivir
  • Indications COVID 2019 infections; SARS-CoV-2 acute respiratory disease
  • Focus Therapeutic Use
  • Acronyms ACTIV-3; TICO
  • Most Recent Events

    • 09 Nov 2023 Results (n=2149) published in the Journal of Infectious Diseases
    • 23 Aug 2023 Status changed from active, no longer recruiting to completed.
    • 18 Aug 2023 This trial has been completed in Denmark (Date of the global end of the trial: 14-Jul-2023), according to the European Clinical Trials Database record.

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