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A Phase 1b/2, Open-Label, Randomized Platform Study Evaluating The Efficacy and Safety of AB928 Based Treatment Combinations in Patients With Metastatic Colorectal Cancer

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Trial Profile

A Phase 1b/2, Open-Label, Randomized Platform Study Evaluating The Efficacy and Safety of AB928 Based Treatment Combinations in Patients With Metastatic Colorectal Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 25 Sep 2024

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At a glance

  • Drugs Etrumadenant (Primary) ; Quemliclustat (Primary) ; Zimberelimab (Primary) ; Bevacizumab; Fluorouracil; Folinic acid; Oxaliplatin; Regorafenib
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ARC-9
  • Sponsors Arcus Biosciences
  • Most Recent Events

    • 02 Aug 2024 Planned End Date changed from 1 Jul 2024 to 1 Oct 2024.
    • 02 Aug 2024 Planned primary completion date changed from 1 Jul 2024 to 1 Oct 2024.
    • 04 Jun 2024 Results (from Cohort B, n=112) assessing safety and efficacy of etrumadenant based treatment combinations in previously treated metastatic colorectal cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology

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