Trial Profile

A Phase II Trial of Neoadjuvant Regorafenib in Combination With Nivolumab and Short-course Radiotherapy in Stage II-III Rectal Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 01 Apr 2026

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At a glance

Drugs Nivolumab (Primary) ; Regorafenib (Primary)
Indications Adenocarcinoma; Rectal cancer
Focus Therapeutic Use
Acronyms REGINA

Most Recent Events

27 Mar 2026 Planned End Date changed from 1 Dec 2030 to 1 Dec 2032.
27 Mar 2026 Planned primary completion date changed from 1 Jan 2026 to 31 Dec 2026.
27 Mar 2026 Status changed from recruiting to active, no longer recruiting.

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