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A Phase 1 Open-Label Study of HER3-DXd (Patritumab Deruxtecan; U3-1402) in Combination With Osimertinib in Subjects With Locally Advanced or Metastatic EGFR-mutated Non-Small Cell Lung Cancer (NSCLC)

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A Phase 1 Open-Label Study of HER3-DXd (Patritumab Deruxtecan; U3-1402) in Combination With Osimertinib in Subjects With Locally Advanced or Metastatic EGFR-mutated Non-Small Cell Lung Cancer (NSCLC)

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 30 Aug 2024

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At a glance

  • Drugs Osimertinib (Primary) ; Patritumab Deruxtecan (Primary)
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Daiichi Sankyo Company

    • Most Recent Events

    • 28 Aug 2024 Status changed from recruiting to active, no longer recruiting.
    • 18 May 2023 Planned number of patients changed from 258 to 280.
    • 18 May 2023 Planned End Date changed from 1 Jan 2024 to 1 Feb 2026.

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