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A Phase 1/2 Study to Evaluate the Safety and Efficacy of a Single Dose of Autologous Clustered Regularly Interspaced Short Palindromic Repeats Gene-edited CD34+ Human Hematopoietic Stem and Progenitor Cells (EDIT-301) in Subjects With Severe Sickle Cell Disease

Trial Profile

A Phase 1/2 Study to Evaluate the Safety and Efficacy of a Single Dose of Autologous Clustered Regularly Interspaced Short Palindromic Repeats Gene-edited CD34+ Human Hematopoietic Stem and Progenitor Cells (EDIT-301) in Subjects With Severe Sickle Cell Disease

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 02 Feb 2025

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At a glance

Most Recent Events

  • 12 Dec 2024 According to an Editas Medicine media release, Company will work closely with the clinical trial sites, regulators, and other parties to determine the path forward for patients enrolled in the trial.
  • 09 Dec 2024 Results as of the data cutoff date (October 29, 2024), presented in the Editas Medicine Media Release.
  • 09 Dec 2024 According to an Editas Medicine media release, data from the study will be presented at at the American Society of Hematology (ASH) Annual Meeting in San Diego, CA, today at 6:00 p.m. PT (9:00 p.m. ET).

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