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A Phase 2a, Open-Label, Single-Arm Study to Investigate the Safety and Efficacy of ATI-450 for the Maintenance of Remission in Patients With Cryopyrin-Associated Periodic Syndrome (CAPS) Previously Managed With Anti-IL-1 Therapy

Trial Profile

A Phase 2a, Open-Label, Single-Arm Study to Investigate the Safety and Efficacy of ATI-450 for the Maintenance of Remission in Patients With Cryopyrin-Associated Periodic Syndrome (CAPS) Previously Managed With Anti-IL-1 Therapy

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 25 Sep 2023

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At a glance

  • Drugs Zunsemetinib (Primary)
  • Indications Cryopyrin-associated periodic syndromes
  • Focus Adverse reactions
  • Sponsors Aclaris Therapeutics

Most Recent Events

  • 26 Mar 2021 Status changed from recruiting to discontinued due to patient enrollment challenges stemming from the COVID-19 pandemic, Aclaris has decided to focus its efforts and resources on other immuno-inflammatory diseases.
  • 25 Feb 2021 According to an Aclaris Therapeutics media release, subject enrollment in this trial was paused due to the COVID-19 pandemic.
  • 24 Nov 2020 Status changed from not yet recruiting to recruiting.

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