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A Multicentre, Open-label, Single-arm, Phase I/II Clinical Study to Evaluate the Safety, Efficacy and Pharmacokinetic Characteristics of Liposomal Mitoxantrone Hydrochloride Injection Combined With Pegaspargase in the Treatment of NKTCL

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Trial Profile

A Multicentre, Open-label, Single-arm, Phase I/II Clinical Study to Evaluate the Safety, Efficacy and Pharmacokinetic Characteristics of Liposomal Mitoxantrone Hydrochloride Injection Combined With Pegaspargase in the Treatment of NKTCL

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 15 Mar 2024

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At a glance

  • Drugs Mitoxantrone liposomal (Primary) ; Pegaspargase (Primary)
  • Indications Extranodal NK-T-cell lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors CSPC ZhongQi Pharmaceutical Technology
  • Most Recent Events

    • 05 Mar 2024 Status changed from not yet recruiting to discontinued because the sponsor has adjusted the R&D strategy.
    • 13 Sep 2022 Results (n=31; data cutoff date: 15 Feb 2022) reporting dose-limiting toxicities, treatment-related adverse events and response data presented at the 47th European Society for Medical Oncology Congress
    • 14 Aug 2020 New trial record

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