Trial Profile

A Phase 2a Open Label Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenous ANX005 in Subjects With, or at Risk for, Manifest Huntington's Disease

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 01 Sep 2026

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At a glance

Drugs Tanruprubart (Primary)
Indications Huntington's disease
Focus Adverse reactions; Pharmacodynamics; Pharmacokinetics; Proof of concept
Sponsors Annexon

Most Recent Events

25 Aug 2026 Actual primary completion date changed from 28 Jan 2022 to 29 Aug 2022.
27 Apr 2023 Final results presented at the 75th Annual Meeting of the American Academy of Neurology 2023.
03 Nov 2022 According to an Annexon media release, data from this study will be presented at Huntingtons Study Group (HSG) 2022 Annual Meeting

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