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Phase II Study of Combination Treatment of Methotrexate, Ibrutinib, and Temozolomide (MIT Regimen) in Patients With Newly Diagnosed Primary CNS Lymphoma

Trial Profile

Phase II Study of Combination Treatment of Methotrexate, Ibrutinib, and Temozolomide (MIT Regimen) in Patients With Newly Diagnosed Primary CNS Lymphoma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 06 Jun 2024

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At a glance

  • Drugs Ibrutinib (Primary) ; Methotrexate (Primary) ; Temozolomide (Primary)
  • Indications CNS cancer; Lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 12 Dec 2023 Results assessing the overall response rate and safety of Methotrexate, Ibrutinib and Temozolomide (MIT) induction treatment were presented at the 65th American Society of Hematology Annual Meeting and Exposition.
  • 06 Apr 2022 Planned primary completion date changed from 1 Dec 2023 to 1 Sep 2022.
  • 14 Dec 2021 Results presented at the 63rd American Society of Hematology Annual Meeting and Exposition

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