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Safety, Tolerability, Pharmacokinetics, and Antitumour Activity of SHR-A1811, in Patients With HER2-expressing Advanced Gastric or Gastroesophageal Junction Adenocarcinoma and Colorectal Cancer: a Phase 1 Study

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Trial Profile

Safety, Tolerability, Pharmacokinetics, and Antitumour Activity of SHR-A1811, in Patients With HER2-expressing Advanced Gastric or Gastroesophageal Junction Adenocarcinoma and Colorectal Cancer: a Phase 1 Study

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 10 Feb 2026

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At a glance

  • Drugs Trastuzumab rezetecan (Primary)
  • Indications Adenocarcinoma; Colorectal cancer; Gastric cancer; Oesophageal cancer
  • Focus Adverse reactions
  • Sponsors Jiangsu Hengrui Medicine Co.

Most Recent Events

  • 06 Feb 2026 Actual Primary Completion Date is 28 Mar 2025.
  • 06 Feb 2026 Status changed from active, no longer recruiting to completed.
  • 19 Mar 2024 Planned End Date changed from 1 Dec 2023 to 1 Dec 2024.

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