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Randomized, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus

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Trial Profile

Randomized, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 13 Jun 2023

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At a glance

  • Drugs EP 547 (Primary)
  • Indications Pruritus
  • Focus Adverse reactions; First in man
  • Sponsors Escient Pharmaceuticals

    • Most Recent Events

    • 30 Mar 2022 Status changed from active, no longer recruiting to completed.
    • 18 Mar 2022 Pharmacokinetic modeling of Ep547 and simulations of exposure in hepatic impairment presented at the 123rd Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics
    • 15 Nov 2021 Results presented at The Liver Meeting 2021: 72nd Annual Meeting of the American Association for the Study of Liver Diseases
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