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Trial Profile

A Randomized Phase 2 Trial of Encorafenib + Binimetinib + Nivolumab vs Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 20 Aug 2024

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At a glance

Drugs Binimetinib (Primary) ; Encorafenib (Primary) ; Ipilimumab (Primary) ; Nivolumab (Primary)
Indications Acral lentiginous melanoma; Brain metastases; Malignant melanoma; Skin cancer
Focus Therapeutic Use

Most Recent Events

06 Jun 2023 The protocol was amended to to exclude patients with asymptomatic MBM.
06 Jun 2023 Trial design presented at the 59th Annual Meeting of the American Society of Clinical Oncology.
06 Nov 2020 Status changed from not yet recruiting to recruiting.

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