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Double-Blind, Randomized, Placebo-controlled, Safety and Efficacy Trial of BHV-3500 (Zavegepant) Intranasal for the Acute Treatment of Migraine

Trial Profile

Double-Blind, Randomized, Placebo-controlled, Safety and Efficacy Trial of BHV-3500 (Zavegepant) Intranasal for the Acute Treatment of Migraine

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 15 Jun 2023

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At a glance

  • Drugs Zavegepant (Primary)
  • Indications Migraine
  • Focus Registrational; Therapeutic Use
  • Sponsors Biohaven Pharmaceuticals; Pfizer

Most Recent Events

  • 27 Apr 2023 Results presented at the 75th Annual Meeting of the American Academy of Neurology 2023
  • 27 Apr 2023 Pooled data (N=2061) from NCT03872453, NCT04571060 presented at the 75th Annual Meeting of the American Academy of Neurology 2023.
  • 27 Apr 2023 Results of post-hoc subgroup pooled analysis (N=2061; zavegepant n=1014, placebo n=1047) from NCT03872453 and NCT04571060 assessing the influence of attack frequency on the efficacy of zavegepant nasal spray in the acute treatment of migraine, presented at the 75th Annual Meeting of the American Academy of Neurology 2023.

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