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RINGSIDE: A Phase 2/3, Randomized, Multicenter Study to Evaluate AL102 in Patients With Progressing Desmoid Tumors

Trial Profile

RINGSIDE: A Phase 2/3, Randomized, Multicenter Study to Evaluate AL102 in Patients With Progressing Desmoid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase II/III

Latest Information Update: 27 Apr 2026

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At a glance

  • Drugs Varegacestat (Primary)
  • Indications Fibroma
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms RINGSIDE
  • Sponsors Ayala Pharmaceuticals; Immunome

Most Recent Events

  • 21 Apr 2026 According to an Immunome media release, data from RINGSIDE trial of varegacestat has been selected for presentation in an oral abstract session at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place May 29-June 2, 2026, in Chicago.
  • 03 Mar 2026 Results presented in the Immunome media release.
  • 15 Dec 2025 According to an Immunome media release, company announced it will host a conference call and webcast on Monday, December 15, 2025, at 8:30 a.m. ET to present topline results from the global pivotal phase 3 RINGSIDE trial of varegacestat in patients with progressing desmoid tumors.

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