Trial Profile

RINGSIDE: A Phase 2/3, Randomized, Multicenter Study to Evaluate AL102 in Patients With Progressing Desmoid Tumors

Status: Active, no longer recruiting

Phase of Trial: Phase II/III

Latest Information Update: 24 Sep 2025

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At a glance

Drugs Varegacestat (Primary)
Indications Fibroma
Focus Adverse reactions; Registrational; Therapeutic Use
Acronyms RINGSIDE
Sponsors Ayala Pharmaceuticals; Immunome

Most Recent Events

06 Aug 2025 According to an Immunome media release, Subgroup Analysis of the Phase 2 Part of the RINGSIDE Phase 2/3 Trial of Varegacestat for Treatment of Desmoid Tumors presented at 2025 ASCO Annual Meeting in June 2025.
06 Aug 2025 According to an Immunome media release, company expects to report topline data from this Phase 3 RINGSIDE Part B study before the end of 2025.
13 Jan 2025 According to an Immunome media release, Immunome expects to report topline data in the second half of 2025.

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