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A Phase 1b/2 Study of the Combination of Pepinemab and Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

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Trial Profile

A Phase 1b/2 Study of the Combination of Pepinemab and Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 03 Jul 2024

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At a glance

  • Drugs Pembrolizumab (Primary) ; Pepinemab (Primary)
  • Indications Carcinoma; Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Squamous cell cancer
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Acronyms KEYNOTE B84
  • Sponsors Vaccinex

    • Most Recent Events

    • 04 Jun 2024 Results assessing correlative and spatial biomarker analysis presented at the 60th Annual Meeting of the American Society of Clinical Oncology.
    • 26 Feb 2024 Planned End Date changed from 4 Sep 2023 to 31 Dec 2024.
    • 26 Feb 2024 Planned primary completion date changed from 4 Sep 2023 to 31 Dec 2024.

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