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A Phase 1b Open-label Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Administration of Blinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precursor Acute Lymphoblastic Leukemia (ALL)

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A Phase 1b Open-label Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Administration of Blinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precursor Acute Lymphoblastic Leukemia (ALL)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 09 Apr 2024

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At a glance

  • Drugs Blinatumomab (Primary) ; Zeluvalimab (Primary) ; Dexamethasone; Dexamethasone
  • Indications Precursor B-cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions
  • Sponsors Amgen

    • Most Recent Events

    • 24 Jan 2023 Status changed from active, no longer recruiting to completed.
    • 07 Nov 2022 Planned End Date changed from 30 Jun 2023 to 23 Jan 2023.
    • 07 Nov 2022 Planned primary completion date changed from 30 Jun 2023 to 23 Jan 2023.

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