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A Phase 1 Dose Escalation and Expanded Cohort Study of P-MUC1C-ALLO1 in Adult Subjects With Advanced or Metastatic Solid Tumors

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Trial Profile

A Phase 1 Dose Escalation and Expanded Cohort Study of P-MUC1C-ALLO1 in Adult Subjects With Advanced or Metastatic Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Sep 2024

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At a glance

  • Drugs P-MUC1C-ALLO1 (Primary)
  • Indications Colorectal cancer; Gastric cancer; Head and neck cancer; HER2 negative breast cancer; Nasopharyngeal cancer; Non-small cell lung cancer; Oesophageal cancer; Ovarian cancer; Pancreatic cancer; Prostate cancer; Renal cell carcinoma; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Poseida Therapeutics
  • Most Recent Events

    • 19 Sep 2024 Planned number of patients changed from 100 to 180.
    • 14 May 2024 According to a Poseida Therapeutics media release, company is exploring higher lymphodepletion regimens in its Phase 1 clinical trial of P-MUC1C-ALLO1 for solid tumors.
    • 07 Mar 2024 According to a Poseida Therapeutics media release, company plans to review initial clinical findings from the Phase 1 clinical trial in solid tumors at AACR related to cell expansion and lymphodepletion regimens anticipated to take place on April 8, 2024, 9:00 AM to 12:30 PM PT. Company plans to present a more fulsome clinical update at an appropriate forum in the second half of 2024.

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