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A Phase 1 Trial of RRx-001 in Combination With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors

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Trial Profile

A Phase 1 Trial of RRx-001 in Combination With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 05 Aug 2024

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At a glance

  • Drugs Irinotecan (Primary) ; Nibrozetone (Primary) ; Temozolomide (Primary)
  • Indications CNS cancer; Nervous system neoplasms; Solid tumours
  • Focus Adverse reactions
  • Acronyms PIRATE
  • Sponsors EpicentRx
  • Most Recent Events

    • 01 Aug 2024 Status changed from active, no longer recruiting to discontinued, due to low enrolment.
    • 22 Mar 2024 Planned End Date changed from 1 Mar 2024 to 31 Dec 2024.
    • 22 Mar 2024 Planned primary completion date changed from 1 Dec 2023 to 31 Dec 2024.

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