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Effect of Atazanavir-ritonavir on the Pharmacokinetics and Toxicity of Lumefantrine in People Living With HIV Attending Lagos University Teaching Hospital

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Trial Profile

Effect of Atazanavir-ritonavir on the Pharmacokinetics and Toxicity of Lumefantrine in People Living With HIV Attending Lagos University Teaching Hospital

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 02 Nov 2021

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At a glance

  • Drugs Atazanavir/ritonavir (Primary) ; Artemether/lumefantrine
  • Indications HIV infections
  • Focus Adverse reactions; Pharmacokinetics

Most Recent Events

  • 23 Mar 2021 Primary endpoint has not been met. (Maximum plasma concentration (Cmax) of lumefantrine), as per results published in the European Journal of Clinical Pharmacology
  • 23 Mar 2021 Primary endpoint has not been met. (Drug exposure (Area under the curve) of lumefantrine), as per results published in the European Journal of Clinical Pharmacology
  • 23 Mar 2021 Primary endpoint has been met. (Day 7 lumefantrine concentration), as per results published in the European Journal of Clinical Pharmacology

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