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Phase I Trial With Expansion Cohort of DNA-PK Inhibition and IMRT in Cisplatin-Ineligible Patients With Stage 3-4 Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC)

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Trial Profile

Phase I Trial With Expansion Cohort of DNA-PK Inhibition and IMRT in Cisplatin-Ineligible Patients With Stage 3-4 Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC)

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Sep 2025

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At a glance

  • Drugs Peposertib (Primary)
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Squamous cell cancer
  • Focus Adverse reactions

Most Recent Events

  • 03 Jul 2025 Planned End Date changed from 31 Jul 2025 to 30 Sep 2025.
  • 03 Jul 2025 Planned primary completion date changed from 31 Jul 2025 to 30 Sep 2025.
  • 07 Jan 2025 Status changed from recruiting to active, no longer recruiting.

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