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Phase I Trial With Expansion Cohort of DNA-PK Inhibition and IMRT in Cisplatin-Ineligible Patients With Stage 3-4 Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC)

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Trial Profile

Phase I Trial With Expansion Cohort of DNA-PK Inhibition and IMRT in Cisplatin-Ineligible Patients With Stage 3-4 Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 14 Aug 2024

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At a glance

  • Drugs Peposertib (Primary)
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Squamous cell cancer
  • Focus Adverse reactions

    • Most Recent Events

    • 21 May 2024 Status changed from suspended to recruiting.
    • 01 May 2024 Status changed from recruiting to suspended due to a DLT assessment specified in protocol.
    • 06 Apr 2023 Planned End Date changed from 24 Jul 2023 to 31 Jul 2025.

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