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Single Patient Protocol: A Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated or Viral Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab

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Single Patient Protocol: A Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated or Viral Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 02 Nov 2021

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At a glance

  • Drugs Pembrolizumab (Primary) ; Aldesleukin; Antibacterials; Antifungals; Antivirals; Cyclophosphamide; Filgrastim; Fludarabine; TCR-transduced lymphocytes
  • Indications Anal cancer; Cancer; Squamous cell cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 29 Jan 2021 Planned initiation date changed from 3 Feb 2021 to 27 Jan 2021.
    • 29 Jan 2021 Status changed from recruiting to discontinued as subject no longer able to participate in this single patient study.
    • 28 Jan 2021 Planned initiation date (estimated date for recruitment of the first subject) changed to 3 Feb 2021.

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