A Phase I, Open-label Multi-dose Two-part Study to Characterize the Effects of a Strong CYP3A4 Inhibitor and a Strong CYP3A4 Inducer on the Steady-State Pharmacokinetics of Tazemetostat (EPZ-6438) in Subjects With Advanced Malignancies

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 28 Aug 2024

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At a glance

Drugs Tazemetostat (Primary) ; Itraconazole; Rifampicin
Indications Solid tumours
Focus Pharmacokinetics
Sponsors Epizyme

Most Recent Events

25 May 2023 Status changed from active, no longer recruiting to completed.
24 Apr 2023 Planned End Date changed from 30 Dec 2023 to 3 May 2023.
20 May 2022 Status changed from recruiting to active, no longer recruiting.

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