Trial Profile

A Phase 1, First-in-Human, Dose Escalation Study of the JNJ-75348780 Bispecific Antibody Targeting CD3 and CD22 in Participants With NHL and CLL

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 03 Jul 2025

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At a glance

Drugs JNJ-75348780 (Primary) ; JNJ-75348780 (Primary)
Indications Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
Focus Adverse reactions; First in man
Sponsors Janssen Research & Development

Most Recent Events

26 Jun 2025 Planned End Date changed from 31 May 2025 to 31 Oct 2025.
26 Jun 2025 Planned primary completion date changed from 4 Apr 2025 to 30 Sep 2025.
05 Dec 2024 Planned End Date changed from 9 May 2025 to 31 May 2025.

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