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Safety and Preliminary Efficacy of Epcoritamab (GEN3013; DuoBody-CD3×CD20) in Japanese Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma - A Phase 1/2, Open-Label, Dose-Escalation Trial With Expansion Cohorts

Trial Profile

Safety and Preliminary Efficacy of Epcoritamab (GEN3013; DuoBody-CD3×CD20) in Japanese Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma - A Phase 1/2, Open-Label, Dose-Escalation Trial With Expansion Cohorts

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 05 Sep 2025

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At a glance

  • Drugs Epcoritamab (Primary)
  • Indications B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Acronyms EPCORE™ NHL-3
  • Sponsors AbbVie; Genmab

Most Recent Events

  • 29 May 2025 Planned End Date changed from 1 Sep 2025 to 1 Sep 2027.
  • 29 May 2025 Planned primary completion date changed from 1 Sep 2025 to 1 Sep 2027.
  • 14 May 2025 According to Genmab media release, data from this study will be presented at the 30th European Hematology Association (EHA) Congress, being held in Milan, Italy, and virtually, June 12-15, 2025.

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