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A Multi-Center, Randomized, Double-Blind, Dose-Ranging, Placebo-Controlled, Proof of Concept, Adaptive, Phase 1b Clinical Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Orally Administered TERN-201 in Patients With Presumed Non-Cirrhotic Non-Alcoholic Steatohepatitis (NASH)

Trial Profile

A Multi-Center, Randomized, Double-Blind, Dose-Ranging, Placebo-Controlled, Proof of Concept, Adaptive, Phase 1b Clinical Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Orally Administered TERN-201 in Patients With Presumed Non-Cirrhotic Non-Alcoholic Steatohepatitis (NASH)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 10 Jun 2024

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At a glance

  • Drugs TERN 201 (Primary)
  • Indications Non-alcoholic steatohepatitis
  • Focus Adverse reactions; Proof of concept
  • Acronyms AVIATION
  • Sponsors Terns Pharmaceuticals

Most Recent Events

  • 24 Jun 2023 Results of pooled analysis from LIFT and AVIATION presented at the European Association for the Study of the Liver Congress 2023
  • 29 Sep 2022 Status changed from active, no longer recruiting to completed.
  • 26 Jun 2022 Interim results (n=30) from Part 1 of Phase 1b portion of this trial in patients with NASH presented at The International Liver Congress 2022

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