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Randomized Phase II Clinical Trial of Olaparib + Pembrolizumab vs. Olaparib Alone as Maintenance Therapy in Metastatic Pancreatic Cancer Patients With Germline BRCA1 or BRCA2 Mutations

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Trial Profile

Randomized Phase II Clinical Trial of Olaparib + Pembrolizumab vs. Olaparib Alone as Maintenance Therapy in Metastatic Pancreatic Cancer Patients With Germline BRCA1 or BRCA2 Mutations

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 03 Sep 2024

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At a glance

  • Drugs Olaparib (Primary) ; Pembrolizumab (Primary)
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 06 Jun 2023 According to trial design presented at the 59th Annual Meeting of the American Society of Clinical Oncology, as of Feb 2023, 26 participants have been accrued.
    • 06 Jun 2023 Trial design presented at the 59th Annual Meeting of the American Society of Clinical Oncology
    • 17 Jan 2021 Planned number of patients changed from 88 to 78, as per Trial design presented at the 2021 Gastrointestinal Cancers Symposium

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