A Pharmacodynamics-Driven Trial of Talazoparib, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Aberrations in Genes Involved in DNA Damage Response
Latest Information Update: 21 Aug 2026
At a glance
- Drugs Talazoparib (Primary)
- Indications Advanced breast cancer; Gastric cancer; HER2 positive breast cancer; Ovarian cancer; Pancreatic cancer; Prostate cancer; Solid tumours
- Focus Pharmacodynamics; Pharmacogenomic
Most Recent Events
- 11 Aug 2026 Planned End Date changed from 14 Jul 2027 to 27 Jul 2027.
- 16 Jul 2026 Planned End Date changed from 1 Dec 2026 to 14 Jul 2027.
- 16 Jul 2026 Status changed from recruiting to active, no longer recruiting.