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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Combination of PI3Kδ Inhibitor Parsaclisib and Ruxolitinib in Participants With Myelofibrosis

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Trial Profile

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Combination of PI3Kδ Inhibitor Parsaclisib and Ruxolitinib in Participants With Myelofibrosis

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 24 Oct 2025

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At a glance

  • Drugs Parsaclisib (Primary) ; Ruxolitinib (Primary)
  • Indications Essential thrombocythaemia; Myelofibrosis; Polycythaemia vera
  • Focus Registrational; Therapeutic Use
  • Acronyms LIMBER-313
  • Sponsors Incyte Corporation

Most Recent Events

  • 04 Oct 2024 Planned End Date changed from 31 Jul 2024 to 15 Nov 2024.
  • 04 Oct 2024 Planned End Date changed from 31 Jul 2024 to 15 Nov 2024.
  • 13 May 2024 Planned End Date changed from 30 Apr 2024 to 31 Jul 2024.

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