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A retrospective, single center study analysing strategy of Pre-transplant myeloid and immune suppression, upfront plerixafor mobilization and post-transplant cyclophosphamide in sickle cell disease

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Trial Profile

A retrospective, single center study analysing strategy of Pre-transplant myeloid and immune suppression, upfront plerixafor mobilization and post-transplant cyclophosphamide in sickle cell disease

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 18 Sep 2020

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At a glance

  • Drugs Antithymocyte globulin (Primary) ; Azathioprine (Primary) ; Busulfan (Primary) ; Cyclophosphamide (Primary) ; Dexamethasone (Primary) ; Fludarabine (Primary) ; Granulocyte colony-stimulating factors (Primary) ; Hydroxycarbamide (Primary) ; Mycophenolate mofetil (Primary) ; Mycophenolate sodium (Primary) ; Plerixafor (Primary) ; Sirolimus (Primary) ; Thiotepa (Primary) ; Antimalarials; Cotrimoxazole; Fluconazole; Levetiracetam; Penicillins; Valaciclovir
  • Indications Graft-versus-host disease; Sickle cell anaemia; Transplant rejection
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 18 Sep 2020 New trial record
    • 15 Sep 2020 Results published in the Bone Marrow Transplantation

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