Trial Profile

Phase I Trial of DNA-PK Inhibitor (PEPOSERTIB ) in Combination With Radiation and Adjuvant Temozolomide in Newly Diagnosed MGMT Unmethylated and Recurrent Glioblastoma

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 02 Jul 2026

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At a glance

Drugs Peposertib (Primary) ; Temozolomide
Indications Glioblastoma; Glioma; Gliosarcoma
Focus Adverse reactions; Biomarker; Pharmacokinetics

Most Recent Events

29 Jun 2026 Status changed from recruiting to active, no longer recruiting.
28 Oct 2025 Planned End Date changed from 30 Oct 2025 to 31 Dec 2027.
28 Oct 2025 Planned primary completion date changed from 30 Oct 2025 to 31 Dec 2027.

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