Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

A Randomised, Double-blind, Placebo Controlled, First-in-human Study to Investigate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Response of SLN360 in Subjects With Elevated Lipoprotein(a)

Next Previous
Trial Profile

A Randomised, Double-blind, Placebo Controlled, First-in-human Study to Investigate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Response of SLN360 in Subjects With Elevated Lipoprotein(a)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 14 Aug 2024

Price :
$35 *
Note:
  • Adis is an information provider.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our trial profile at the time of purchase.
  • A link to download a PDF version of the trial profile will be included in your email receipt.

At a glance

  • Drugs Zerlasiran (Primary)
  • Indications Cardiovascular disorders; Dyslipidaemias; Hyperlipidaemia
  • Focus Adverse reactions; First in man
  • Acronyms APOLLO
  • Sponsors Silence Therapeutics

Most Recent Events

  • 08 Apr 2024 According to a Silence Therapeutics media release, results from the single ascending dose portion of the trial in healthy participants were previously published in the April 2022 issue of JAMA.
  • 08 Apr 2024 According to a silence therapeutics media release, additional results from the APOLLO phase 1 study of zerlasiran (SLN360) in subjects with baseline lipoprotein(a), or Lp(a), levels at or over 150 nmol/L were published in the Journal of the American Medical Association (JAMA).
  • 01 Nov 2023 According to silence therapeutics media release, the company plans to present further results from the APOLLO multiple dose study at a future cardiovascular medicines conference.

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top