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A Phase 1 Study to Evaluate Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for Patients With MMP2+ Recurrent or Progressive Glioblastoma

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Trial Profile

A Phase 1 Study to Evaluate Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for Patients With MMP2+ Recurrent or Progressive Glioblastoma

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 01 Sep 2026

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At a glance

  • Drugs CHM 1101 (Primary)
  • Indications Glioblastoma; Glioma
  • Focus Adverse reactions

Most Recent Events

  • 24 Aug 2026 Planned End Date changed from 11 May 2027 to 20 Jul 2028.
  • 24 Aug 2026 Planned primary completion date changed from 11 May 2027 to 20 Aug 2027.
  • 01 Jul 2026 Planned End Date changed from 9 Jun 2026 to 11 May 2027.

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