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A Phase 1/1b Trial of MRTX849 in Combination With BI 1701963 in Patients With Advanced Solid Tumors With KRAS G12C Mutation

Trial Profile

A Phase 1/1b Trial of MRTX849 in Combination With BI 1701963 in Patients With Advanced Solid Tumors With KRAS G12C Mutation

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 18 Dec 2024

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At a glance

  • Drugs Adagrasib (Primary) ; BI 1701963 (Primary)
  • Indications Colorectal cancer; Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; Pharmacokinetics
  • Acronyms KRYSTAL 14; KRYSTAL-014
  • Sponsors Mirati Therapeutics

Most Recent Events

  • 18 Dec 2024 Status changed from completed to discontinued. (The decision was made to terminate this study to further enrollment, as of 08 March 2022. The decision was made primarily due to a change in development strategy. )
  • 06 Dec 2022 Status changed from active, no longer recruiting to completed.
  • 04 Apr 2022 Status changed from recruiting to active, no longer recruiting.

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