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Evaluation of the Efficacy and Safety of Rifaximin in Combination With N-acetylcysteine (NAC) in Adult Patients With Irritable Bowel Syndrome With Diarrhea

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Trial Profile

Evaluation of the Efficacy and Safety of Rifaximin in Combination With N-acetylcysteine (NAC) in Adult Patients With Irritable Bowel Syndrome With Diarrhea

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 30 Mar 2023

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At a glance

  • Drugs Acetylcysteine (Primary) ; Rifaximin (Primary)
  • Indications Irritable bowel syndrome
  • Focus Proof of concept; Therapeutic Use

    • Most Recent Events

    • 06 Mar 2023 Status changed from active, no longer recruiting to completed.
    • 01 Dec 2022 Results from NCT03763175 and NCT04557215; evaluating distinct gut microtypes linked to breath gas patterns in IBS-C and IBS-D subjects, published in the American Journal of Gastroenterology
    • 03 Nov 2021 Planned End Date changed from 1 Sep 2021 to 31 Jan 2022.

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