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A Phase 2, Randomized, Open-Label, Multicenter Study to Evaluate Safety and Efficacy of Single Agent Selinexor Versus Treatment of Physician's Choice in Patients With Previously Treated Myelofibrosis

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Trial Profile

A Phase 2, Randomized, Open-Label, Multicenter Study to Evaluate Safety and Efficacy of Single Agent Selinexor Versus Treatment of Physician's Choice in Patients With Previously Treated Myelofibrosis

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 20 May 2025

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At a glance

  • Drugs Selinexor (Primary) ; Anagrelide; Androgen receptor modulators; Colony-stimulating factor receptor modulators; Corticosteroid; Fedratinib; Hydroxycarbamide; Interferon; Ruxolitinib
  • Indications Essential thrombocythaemia; Myelofibrosis; Polycythaemia vera
  • Focus Therapeutic Use
  • Acronyms XPORT-MF035
  • Sponsors Karyopharm Therapeutics

Most Recent Events

  • 14 May 2025 According to a Karyopharm Therapeutics media release, data from this study will be presented as a poster presentation at the 2025 European Hematology Association Annual Meeting (EHA) being held June 12-15 in Milan, Italy.
  • 08 May 2025 Results presented in the Karyopharm Therapeutics Media Release.
  • 13 Sep 2024 This trial has been completed in Poland, according to European Clinical Trials Database.

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