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A Phase I/II Open Label Single Centre Trial to Assess the Safety, Tolerability and Efficacy of Single Dose Neoadjuvant Anti-CLEVER-1 Antibody Bexmarilimab in Localised Renal Cell and Colon Carcinoma (Macrophage Antibody To Inhibit Immune Suppression in RENAl Cell and COLon Carcinomas)

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Trial Profile

A Phase I/II Open Label Single Centre Trial to Assess the Safety, Tolerability and Efficacy of Single Dose Neoadjuvant Anti-CLEVER-1 Antibody Bexmarilimab in Localised Renal Cell and Colon Carcinoma (Macrophage Antibody To Inhibit Immune Suppression in RENAl Cell and COLon Carcinomas)

Status: Withdrawn prior to enrolment
Phase of Trial: Phase I/II

Latest Information Update: 12 Sep 2023

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At a glance

  • Drugs Bexmarilimab (Primary)
  • Indications Adenocarcinoma; Clear cell sarcoma; Colon cancer; Renal cell carcinoma
  • Focus Adverse reactions
  • Acronyms MATINS RENACOL; RENACOL
  • Sponsors Faron Pharmaceuticals

    • Most Recent Events

    • 05 May 2022 Status changed from recruiting to withdrawn prior to enrolment, because no patients have been enrolled in RENACOL, and safety and tolerability data is rapidly accumulating in another ongoing study, sponsor considered that RENACOL study is no longer needed to assess the safety profile of bexmarilimab.
    • 16 Jun 2021 Status changed from planning to recruiting.
    • 28 Sep 2020 New trial record

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