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A single arm double-blind placebo controlled cross-over trial of Aprepitant for the treatment of cough in lung cancer: CALC Trial

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A single arm double-blind placebo controlled cross-over trial of Aprepitant for the treatment of cough in lung cancer: CALC Trial

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 18 Apr 2022

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At a glance

  • Drugs Aprepitant (Primary)
  • Indications Cough
  • Focus Therapeutic Use
  • Acronyms CALC Trial

    • Most Recent Events

    • 01 Apr 2022 Results assessing systemic absorption from dermal application during PDT, ALA and its key active metabolite protoporphyrin IX (PpIX) were analyzed in 2 trials (NCT04319159 & EudraCT2013-000139-28) published in the Clinical Pharmacology in Drug Development.
    • 28 Sep 2020 New trial record
    • 23 Sep 2020 Primary endpoint ( awake cough frequency ) has been met, as per Results published in the American Journal of Respiratory and Critical Care Medicine

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