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Phase II Study of Trastuzumab-Deruxtecan (T-DX; DS-8201a) in HER2-positive Breast Cancer Patients with newly diagnosed or progressing Brain Metastases

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Trial Profile

Phase II Study of Trastuzumab-Deruxtecan (T-DX; DS-8201a) in HER2-positive Breast Cancer Patients with newly diagnosed or progressing Brain Metastases

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 21 Feb 2024

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At a glance

  • Drugs Trastuzumab-deruxtecan (Primary)
  • Indications Advanced breast cancer; Brain metastases; HER2 positive breast cancer
  • Focus Therapeutic Use
  • Acronyms TUXEDO-1
  • Most Recent Events

    • 10 May 2023 Status changed from active, no longer recruiting to completed.
    • 13 Mar 2023 Planned primary completion date changed from 28 Jul 2022 to 28 Jul 2023.
    • 13 Sep 2022 Results assessing quality-of-life and neurocognitive function presented at the 47th European Society for Medical Oncology Congress

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