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A Phase I/II Study Exploring the Safety and Activity of Trifluridine/Tipiracil in Combination With Capecitabine and Bevacizumab in Metastatic Colorectal Cancer Patients

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Trial Profile

A Phase I/II Study Exploring the Safety and Activity of Trifluridine/Tipiracil in Combination With Capecitabine and Bevacizumab in Metastatic Colorectal Cancer Patients

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 20 Aug 2026

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At a glance

  • Drugs Bevacizumab (Primary) ; Capecitabine (Primary) ; Tipiracil/trifluridine (Primary)
  • Indications Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TriComB

Most Recent Events

  • 20 May 2026 Planned End Date changed from 1 Mar 2026 to 1 Nov 2026.
  • 08 Jan 2026 Planned End Date changed from 1 Dec 2025 to 1 Mar 2026.
  • 06 Jun 2025 Planned End Date changed from 1 May 2025 to 1 Dec 2025.

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