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A Phase 2 Randomized, Open-label, Parallel-group, Multicenter Study to Assess Intrahepatic and Peripheral Changes of Immunologic and Virologic Markers in Response to Combination Regimens Containing JNJ-73763989 and Nucleos(t)Ide Analog With or Without JNJ-56136379 in Patients With Chronic Hepatitis B Virus Infection

Trial Profile

A Phase 2 Randomized, Open-label, Parallel-group, Multicenter Study to Assess Intrahepatic and Peripheral Changes of Immunologic and Virologic Markers in Response to Combination Regimens Containing JNJ-73763989 and Nucleos(t)Ide Analog With or Without JNJ-56136379 in Patients With Chronic Hepatitis B Virus Infection

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 May 2025

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At a glance

  • Drugs Bersacapavir (Primary) ; Entecavir (Primary) ; JNJ 73763989 (Primary) ; Tenofovir alafenamide (Primary) ; Tenofovir disoproxil fumarate (Primary) ; Peginterferon alfa-2a
  • Indications Hepatitis B
  • Focus Therapeutic Use
  • Acronyms INSIGHT
  • Sponsors Janssen Sciences Ireland UC

Most Recent Events

  • 20 Feb 2024 This study has been completed in France, according to European Clinical Trials Database record.
  • 08 Feb 2024 Status changed from active, no longer recruiting to completed.
  • 02 Dec 2023 This trial has been completed in Belgium, according to the European Clinical Trials Database record.

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