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A Modular Phase 2a Multicentre Open-Label Study to Investigate DNA-damage Response Agents (or Combinations) in Patients With Advanced Cancer Whose Tumours Contain Molecular Alterations (PLANETTE)

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Trial Profile

A Modular Phase 2a Multicentre Open-Label Study to Investigate DNA-damage Response Agents (or Combinations) in Patients With Advanced Cancer Whose Tumours Contain Molecular Alterations (PLANETTE)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 02 Sep 2024

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At a glance

  • Drugs Ceralasertib (Primary)
  • Indications Advanced breast cancer; Endometrial cancer; Prostate cancer; Solid tumours
  • Focus Therapeutic Use
  • Acronyms PLANETTE
  • Sponsors AstraZeneca; AstraZeneca AB

    • Most Recent Events

    • 25 Jun 2024 Planned End Date changed from 5 Feb 2024 to 7 Feb 2025.
    • 10 Apr 2024 Results (n=45) assessing Efficacy and safety of ceralasertib in patients with ATM-altered advanced solid tumors or metastatic castration-resistant prostate cancer presented at the 115th Annual Meeting of the American Association for Cancer Research
    • 14 Sep 2023 Planned End Date changed from 29 Dec 2023 to 5 Feb 2024.

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