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A Randomized, Open-label, Three-period Crossover Clinical Trial to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunteers

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A Randomized, Open-label, Three-period Crossover Clinical Trial to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 15 Mar 2023

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At a glance

  • Drugs Atovaquone/proguanil (Primary) ; Esomeprazole (Primary) ; Tegoprazan (Primary) ; Vonoprazan (Primary)
  • Indications Bleeding ulcer; Duodenal ulcer; Erosive oesophagitis; Gastric ulcer; Gastro-oesophageal reflux; Helicobacter infections; Jejunal ulcer; Malaria; NSAID-induced ulcer; Peptic ulcer; Reflux oesophagitis; Stress ulcer; Zollinger-Ellison syndrome
  • Focus Pharmacokinetics

    • Most Recent Events

    • 10 Mar 2023 Results assessing the effect of tegoprazan on the pharmacokinetics of proguanil, compared with vonoprazan or esomeprazole, published in the Clinical Pharmacokinetics.
    • 23 Sep 2021 Status changed from recruiting to completed.
    • 16 Mar 2021 Status changed from not yet recruiting to recruiting.

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