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A First-In-Human Phase I, Open Label, Safety and Tolerability Study of Escalating Multiple Doses of Intratumoral MQ710, a Multi-Transgene Expressing Modified Vaccinia Virus Ankara-Based Virotherapy, Alone and in Combination With the Systemic Checkpoint Inhibitor Pembrolizumab in Solid Tumors

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A First-In-Human Phase I, Open Label, Safety and Tolerability Study of Escalating Multiple Doses of Intratumoral MQ710, a Multi-Transgene Expressing Modified Vaccinia Virus Ankara-Based Virotherapy, Alone and in Combination With the Systemic Checkpoint Inhibitor Pembrolizumab in Solid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 29 Jul 2024

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At a glance

  • Drugs MQ 710 (Primary) ; Pembrolizumab (Primary)
  • Indications Adenocarcinoma; Basal cell cancer; Carcinoma; Extramammary Paget disease; Haemangiosarcoma; Head and neck cancer; Kaposi's sarcoma; Malignant melanoma; Merkel cell carcinoma; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man

    • Most Recent Events

    • 25 Jul 2024 Planned number of patients changed from 56 to 5.
    • 25 Jul 2024 Status changed from planning to active, no longer recruiting.
    • 18 May 2023 Planned End Date changed from 4 May 2025 to 4 May 2028.

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