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A Multicenter, Phase 1, Open-label, Dose-escalation and Expansion Study of AZD0486, a Bispecific Antibody Targeting CD19 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

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Trial Profile

A Multicenter, Phase 1, Open-label, Dose-escalation and Expansion Study of AZD0486, a Bispecific Antibody Targeting CD19 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 01 Oct 2024

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At a glance

  • Drugs AZD 0486 (Primary)
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Richter's syndrome
  • Focus Adverse reactions; First in man; Pharmacokinetics
  • Sponsors Amgen; AstraZeneca; TeneoBio

    • Most Recent Events

    • 31 Jul 2024 Planned number of patients changed from 206 to 116.
    • 09 May 2024 Planned number of patients changed from 116 to 206.
    • 09 May 2024 Planned End Date changed from 22 Jan 2027 to 15 Jan 2027.

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