Trial Profile

A Multicenter, Phase 1, Open-label, Dose-escalation and Expansion Study of AZD0486, a Bispecific Antibody Targeting CD19 in Subjects With B-Cell Non-Hodgkin Lymphoma

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 22 Jun 2026

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At a glance

Drugs Surovatamig (Primary)
Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Richter's syndrome
Focus Adverse reactions; First in man; Pharmacokinetics
Sponsors Amgen; AstraZeneca; TeneoBio

Most Recent Events

17 Jun 2026 Planned End Date changed from 19 Apr 2028 to 19 Jun 2028.
17 Jun 2026 Planned primary completion date changed from 19 Apr 2028 to 19 Jun 2028.
17 Jun 2026 Status changed from recruiting to active, no longer recruiting.

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