Trial Profile

A Multicenter, Phase 1, Open-label, Dose-escalation and Expansion Study of AZD0486, a Bispecific Antibody Targeting CD19 in Subjects With B-Cell Non-Hodgkin Lymphoma

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 26 Jun 2025

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At a glance

Drugs AZD 0486 (Primary)
Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Richter's syndrome
Focus Adverse reactions; First in man; Pharmacokinetics
Sponsors Amgen; AstraZeneca; TeneoBio

Most Recent Events

15 May 2025 Planned number of patients changed from 231 to 317.
15 May 2025 Planned End Date changed from 15 Jan 2027 to 19 Apr 2028.
15 May 2025 Planned primary completion date changed from 15 Jan 2027 to 19 Apr 2028.

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