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Thyroid Hormone Analog Therapy of Patients With Severe Psychomotor Retardation Caused by Mutations in the MCT8 Thyroid Hormone Transporter: The Triac Trial

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Thyroid Hormone Analog Therapy of Patients With Severe Psychomotor Retardation Caused by Mutations in the MCT8 Thyroid Hormone Transporter: The Triac Trial

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Dec 2024

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At a glance

  • Drugs Tiratricol (Primary)
  • Indications Allan-Herndon-Dudley syndrome
  • Focus Registrational; Therapeutic Use
  • Acronyms Triac; Triac Trial I; TRIAC-1
  • Sponsors Rare Thyroid Therapeutics

    • Most Recent Events

    • 12 Dec 2024 According to a Egetis Therapeutics media release, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion for Emcitate (tiratricol) for the treatment of MCT8 deficiency.The Marketing Authorisation Application for tiratricol is primarily based on results from Triac Trial I.
    • 06 Sep 2024 According to an Egetis Therapeutics media release, data from this study have been published ahead of the 46th Annual Meeting of the European Thyroid Association.
    • 06 Sep 2024 Results published in an Egetis Therapeutics AB Media Release.

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