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Trial Profile

A phase 1b study to evaluate the blood stage antimalarial activity of a single oral dose of tafenoquine in healthy subjects experimentally infected with Plasmodium falciparum

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 21 Feb 2023

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At a glance

  • Drugs Tafenoquine (Primary) ; Artemether/lumefantrine; Artesunate; Atovaquone/proguanil; Piperaquine; Primaquine
  • Indications Falciparum malaria
  • Focus Therapeutic Use
  • Most Recent Events

    • 16 Feb 2023 Results(n=12) assessing blood stage antimalarial activity of tafenoquine in healthy volunteers experimentally infected with Plasmodium falciparum published in the Clinical Infectious Diseases
    • 22 Jun 2022 Results (n=6) assessing transmission blocking activity of low dose tafenoquine in healthy volunteers published in the Clinical Infectious Diseases
    • 30 Oct 2020 Planned initiation date (estimated date for recruitment of the first subject) changed to 3 Nov 2020.

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